一、基本信息

王晓航，男，1991年11月出生，医学博士，讲师，硕士生导师，扬州大学医学院，扬州大学附属医院，邮箱：wangxiaohang@yzu.edu.cn。

二、教育经历

2010.9—2015.7，扬州大学，医学院，临床医学专业，学士

2015.9—2018.7，东南大学，医学院，内科学专业，硕士

2019.3—2022.12，东南大学，医学院，内科学专业，博士

三、研究方向

主要从事糖尿病及其相关并发症防治相关研究。

四、承担项目

1. 国家自然科学基金青年科学基金项目“HIIT运动通过Clec11α/Podoplanin通路促进胰腺星状细胞向β细胞转分化调节糖代谢的机制研究”项目号82500978，2026/01-2028/12，30万，主持。

2. 国家自然科学基金面上基金项目“Podoplanin通过细胞变形介导胰岛星状细胞活化的机制研究”项目号82270848，2023/01-2026/12，50万，项目核心成员。

3. 中华人民共和国科学技术部,重大慢病专项, 2016YFC1305700,糖尿病的危险因素早期识别、早期诊断技术与切点研究, 2016-09至2020-12, 571万元,结题,参与。

4. 扬州大学附属医院高层次人才科研启动基金，项目号2023BS-WXH，2023/05-2026/12，20万，主持

5. 扬州大学高层次人才科研启动基金，项目号137013107/5022，2023/05-2026/12，10万，主持

6. 扬州市“绿扬金凤”人才项目，项目号5022/137013454，2024/06-2027/05，6万，主持

五、代表性论著

1. Wang X, Wang Q, Yuan Y, Ni C, Cai Z, Qiu S, Li T, Chen Y, Wang J, Wang H, Carvalho V, Sun Z, Liu L. Podoplanin-TGF-β1 Autocrine Loop: Pivotal Regulator of Islet Stellate Cell Activation via Cell Deformation, Orchestrating Islet Fibrosis in Diabetes. FASEB J. 2025 Sep 15;39(17):e70970.

2. X. Wang, Q. Wang,Z, Cai,H Wang,C. Ni,X Wang,Knockdown of PDPN in Astrocytes Reduces Hippocampal Inflammation in T2DM Mice.Frontiers in Immunology. 2025 Jan.

3. Ni C,Wang X, Zhou Y, Wang Q, Cai Z, Wang H, Chen Y, Liu Y, Sun Z. Association of oxidative balance score, cardiovascular, and all-cause mortality among patients with type 2 diabetes mellitus. Front Endocrinol (Lausanne). 2024 Aug 20;15:1429662.(并列一作)

4. X. Wang, V. Carvalho, Q. Wang, J. Wang, T. Li, Y. Chen, C. Ni, L. Liu, Y. Yuan, S. Qiu, and Z. Sun, Screening and Identification of Key Genes for Activation of Islet Stellate Cell. Front Endocrinol 12 (2021).

5. X. Wang, X. Wang, V. Carvalho, Q. Wang, T. Li, J. Wang, Y. Chen, C. Ni, S. Liu, and J. Zhang, Prognostic Value of Podoplanin in Various Tumors. Technology in cancer research & treatment 20 (2021) 15330338211038142.

6. X. Wang, W. Li, J. Chen, Y. Chen, and Z. Sun, Screening and identification of key genes for activation of islet stellate cell. Diabetologia 62 (2019) S229-S230.（会议论文）

7. X.H. Wang, W. Li, J. Chen, S. Zhao, S.H. Qiu, H. Yin, V. Carvalho, Y.T. Zhou, R.F. Shi, J.N. Hu, S.Y. Li, M. Nijiati, and Z.L. Sun, A Transcriptional Sequencing Analysis of Islet Stellate Cell and Pancreatic Stellate Cell. J Diabetes Res 2018 (2018).

8. J. Qian, C. Chen,X. Wang, Y. Tan, J. Yang, Y. Yuan, J. Chen, H. Guo, B. Wang, Z. Sun, and Y. Wang, HbA1c combined with glycated albumin or 1,5-anhydroglucitol improves the efficiency of diabetes screening in a Chinese population. Diabetic medicine : a journal of the British Diabetic Association (2021) e14685.

9. Y.T. Zhou, J.M. Zhou, Y.M. Zhang, J. Tang, B. Sun, W. Xu,X.H. Wang, Y. Chen, and Z.L. Sun, Changes in Intestinal Microbiota Are Associated with Islet Function in a Mouse Model of Dietary Vitamin A Deficiency. J Diabetes Res 2020 (2020).

10. Y.T. Zhou, J.M. Zhou, B. Sun, W. Xu, M. Zhong, Y.M. Li, C. He, Y. Chen,X.H. Wang, P.M. Jones, and Z.L. Sun, Vitamin A deficiency causes islet dysfunction by inducing islet stellate cell activation via cellular retinol binding protein 1. Int J Biol Sci 16 (2020) 947-956.

11. X.H. Xu, V. Carvalho,X.H. Wang, S.H. Qiu, and Z.L. Sun, Lipohypertrophy: prevalence, clinical consequence, and pathogenesis. Chin Med J (Engl) 134 (2020) 47-49.

12. Y.L. Chen, W. Li, S.H. Qiu, C. Vladmir, X.H. Xu, X.L. Wang, X. Nian, Q.Y. Chen, Q. Wang, P. Tu, L.H. Zhang, S.J. Yan, K.L. Li, J. Chen, H. Wu, X.Y. Wang,X.H. Wang, J.B. Liu, M. Cai, Z.Y. Wang, B. Wang, and Z.L. Sun, Tea consumption and risk of diabetes in the Chinese population: a multi-centre, cross-sectional study. Brit J Nutr 123 (2020) 428-436.

13. J. Chen, C.H. Wu,X.H. Wang, J.Y. Yu, and Z.L. Sun, The Impact of COVID-19 on Blood Glucose: A Systematic Review and Meta-Analysis. Front Endocrinol 11 (2020).

14. C. Chen,X.H. Wang, Y.Y. Tan, J. Yang, Y.X. Yuan, J. Chen, H.J. Guo, B. Wang, Z.L. Sun, and Y. Wang, Reference intervals for serum 1,5-anhydroglucitol of a population with normal glucose tolerance in Jiangsu Province. J Diabetes 12 (2020) 447-454.

15. Y.T. Zhou, B. Sun, W. Li, J.M. Zhou, F. Gao,X.H. Wang, M. Cai, and Z.L. Sun, Pancreatic Stellate Cells: A Rising Translational Physiology Star as a Potential Stem Cell Type for Beta Cell Neogenesis. Front Physiol 10 (2019).

16. Y.T. Zhou, W. Li, J.M. Zhou, J. Chen,X.H. Wang, M. Cai, F.F. Li, W. Xu, P.O. Carlsson, and Z.L. Sun, Lipotoxicity reduces beta cell survival through islet stellate cell activation regulated by lipid metabolism-related molecules. Exp Cell Res 380 (2019) 1-8.

17. W.C. Wang, J. Zhang, H. Wang,X.H. Wang, and S.B. Liu, Vitamin D deficiency enhances insulin resistance by promoting inflammation in type 2 diabetes. Int J Clin Exp Patho 12 (2019) 1859-1867.

18. R.F. Shi, J. Hu, W. Li, Z.R. Wang, Y. Pan, M. Bai, W.T. Mao,X.H. Wang, M. Zhong, Y. Yuan, O.E. Lau, Z.L. Sun, and S. Zhao, Protective effects of Clec11a in islets against lipotoxicity via modulation of proliferation and lipid metabolism in mice. Exp Cell Res 384 (2019).

19. W. Li, Y.T. Zhou,X.H. Wang, M. Cai, F. Gao, P.O. Carlsson, and Z.L. Sun, A modified in vitro tool for isolation and characterization of rat quiescent islet stellate cells. Exp Cell Res 384 (2019).

20. J. Chen, H.J. Guo, S.X. Yuan, C. Qu, T. Mao, S.H. Qiu, W. Li,X.H. Wang, M. Cai, H. Sun, B. Wang, X.N. Li, and Z.L. Sun, Efficacy of urinary glucose for diabetes screening: a reconsideration. Acta Diabetol 56 (2019) 45-53.

21. W.C. Wang, J. Zhang,X.H. Wang, H. Wang, Q.H. Ren, and Y.K. Li, Effects of melatonin on diabetic nephropathy rats via Wnt/beta-catenin signaling pathway and TGF-beta-Smad signaling pathway. Int J Clin Exp Patho 11 (2018) 2488-2496.

22. W. Li, B. Xie, S.H. Qiu, X. Huang, J. Chen, X.L. Wang, H. Li, Q.Y. Chen, Q. Wang, P. Tu, L.H. Zhang, S.J. Yan, K.L. Li, J. Maimaitiming, X. Nian, M. Liang, Y. Wen, J. Liu, M. Wang, Y.Z. Zhang, L. Ma, H. Wu, X.Y. Wang,X.H. Wang, J.B. Liu, M. Cai, Z.Y. Wang, L. Guo, F.Q. Chen, B. Wang, S. Monica, P.O. Carlsson, and Z.L. Sun, Non-lab and semi-lab algorithms for screening undiagnosed diabetes: A cross-sectional study. Ebiomedicine 35 (2018) 307-316.

23. J. Chen, H.J. Guo, S.H. Qiu, W. Li,X.H. Wang, M. Cai, B. Wang, X.N. Li, and Z.L. Sun, Identification of Newly Diagnosed Diabetes and Prediabetes Using Fasting Plasma Glucose and Urinary Glucose in a Chinese Population: A Multicenter Cross-Sectional Study. Chinese Med J-Peking 131 (2018) 1652-1657.

24. Z.W. Du, J. Chen, H.J. Guo, S.X. Yuan, C. Qu, T. Mao, W. Li,X.H. Wang, M. Cai, B. Wang, Z.L. Sun, and X.N. Li, The optimized cut-off point of HbA1c for diagnosing diabetes is 6.1% in the Jiangsu population. Diabetes-Metab Res 33 (2017)

二、核心期刊：

[1]王倩倩#，王晓航#，邱山虎，孙子林.运动对肥胖相关代谢异常的作用[J].中国实用内科杂志,2022,42(02):102-106

[2]王倩倩#，王晓航#，周潇滢，孙子林等.运动是减重之本[J].中国全科医学，2023,26(28):3471-3476.

六、获奖情况

1. 2024年扬州“绿扬金凤”人才称号

2. 2019欧洲糖尿病年会Travel Grant

3. 2024、2025韩国糖尿病协会年会Travel Grant