一、基本信息

李善义，男，1985年6月出生，博士，讲师，硕士生导师，基础医学系细胞生物学教研室，邮箱：008093@yzu.edu.cn。

二、教育经历

2008.09 – 2010.07,安徽科技学院,食品质量与安全专业,学士

2010.09 – 2013.07,暨南大学,细胞生物学专业,硕士

2014.09 – 2017.07,暨南大学,再生医学专业,博士

2017.08 – 2021.07,美国罗格斯大学，博士后

三、研究方向

天然产物在预防和治疗肿瘤、糖尿病等慢性疾病方面的作用研究

四、承担项目

扬州大学博士科研启动基金，15万，主持。

五、代表性论著

1.Li S, Cai T, Cui S, Liu F, Hu R, Li W. Prostate Cancer, Oxidative Stress, and Antioxidant Phytochemicals: A Brief Review. Current pharmacology reports. 2023;9(6):391-6.

2.Li S, Dina Kuo HC, Wang L, Wu R, Sargsyan D, Kong AN. UVB Drives Metabolic Rewiring and Epigenetic Reprograming and Protection by Sulforaphane in Human Skin Keratinocytes. Chemical research in toxicology. 2022;35(7):1220-33.

3.Li S, Wu R, Wang L, Dina Kuo HC, Sargsyan D, Zheng X, et al. Triterpenoid ursolic acid drives metabolic rewiring and epigenetic reprogramming in treatment/prevention of human prostate cancer. Molecular carcinogenesis. 2022;61(1):111-21.

4.Li S, Kuo HD, Yin R, Wu R, Liu X, Wang L, et al. Epigenetics/epigenomics of triterpenoids in cancer prevention and in health. Biochemical pharmacology. 2020;175:113890.

5.Li S, Yang Y, Sargsyan D, Wu R, Yin R, Kuo HD, et al. Epigenome, Transcriptome, and Protection by Sulforaphane at Different Stages of UVB-Induced Skin Carcinogenesis. Cancer prevention research (Philadelphia, Pa). 2020;13(6):551-62.

6.Li S, Li W, Wang C, Wu R, Yin R, Kuo HC, et al. Pelargonidin reduces the TPA induced transformation of mouse epidermal cells -potential involvement of Nrf2 promoter demethylation. Chemico-biological interactions. 2019; 309:108701.

7.Li S, Li W, Wu R, Yin R, Sargsyan D, Raskin I, et al. Epigenome and transcriptome study of moringa isothiocyanate in mouse kidney mesangial cells induced by high glucose, a potential model for diabetic-induced nephropathy. The AAPS journal. 2019;22(1):8.

8.Li S, Han Y, Lei H, Zeng Y, Cui Z, Zeng Q, et al. In vitro biomimetic platforms featuring a perfusion system and 3D spheroid culture promote the construction of tissue-engineered corneal endothelial layers. Scientific reports. 2017;7(1):777.

9.Li S, Wang C, Dai Y, Yang Y, Pan H, Zhong J, et al. The stimulatory effect of ROCK inhibitor on bovine corneal endothelial cells. Tissue & cell. 2013;45(6):387-96.