一、基本信息

茅怡铭，男，1985年1月出生，医学博士，硕士生导师，就职于苏州九龙医院，邮箱：253992240@qq.com。

二、教育经历

2003.8—2008.6，扬州大学，医学院，临床医学专业，学士

2013.3—2015.12，苏州大学，医学院，外科学专业，硕士

2016.9—2019.6，苏州大学，医学院，临床医学专业，博士

三、研究方向

主要从事肿瘤的基础与临床相关研究

四、承担项目

1. 2022年苏州市医学创新应用研究“I期肺腺癌亚肺叶切除术中淋巴结清扫诱导的免疫微环境改变与临床预后相关性的应用研究”，项目号：SKY2022094，2022/07-2025/06，5万，主持

2. 2023年苏州市苏州市科技发展计划项目“靶向巨噬细胞IL13RA抑制胶质母细胞瘤进展的应用研究”,项目号：SKYD2023032，2023/07-2026/06，2万，主持

3. 2023年单位自筹项目“IL13RA1介导的IL-4/IL-13信号通路活化促进巨噬细胞M2极化在恶性胶质瘤进展中的机制研究”，2023/01-2026/01，20万，主持

五、代表性论著

1.Chen D#,Mao Y#, Ding Q#, Wang W, Zhu F, Chen C*, Chen Y*.Prognostic implications of programmed death ligand 1 expression in resected lung adenocarcinoma: a systematic review and meta-analysis[J].Eur J Cardiothorac Surg.2020,58(5):888-898.doi: 10.1093/ejcts/ezaa172.

2.Chen D#,Mao Y#, Wen J#, Shu J, Ye F, She Y, Ding Q, Shi L, Xue T, Fan M*, Chen Y*, Chen C*Impact of the Extent of Lymph Node Dissection on Precise Staging and Survival in Clinical I-II Pure-Solid Lung Cancer Undergoing Lobectomy.[J].J Natl Compr Canc Netw.2021,19(4):393-402.doi: 10.6004/jnccn.2020.7635.

3. Chen D#, Wang Y#, Zhang X, Ding Q, Wang X, Xue Y, Wang W,Mao Y *, Chen C*, Chen Y*. Characterization of Tumor Microenvironment in Lung Adenocarcinoma Identifies Immune Signatures to Predict Clinical Outcomes and Therapeutic Responses[J].Front Oncol.2021,11:581030.doi: 10.3389/fonc.2021.581030.

4.Mao Y#, Chen D#, Duan S#, Zhao Y, Wu C, Zhu F, Chen C*, Chen Y*.Prognostic impact of pretreatment lymphocyte-to-monocyte ratio in advanced epithelial cancers: a meta-analysis[J].Cancer Cell Int.2018,18:201.doi: 10.1186/s12935-018-0698-5.

5. Chen D#,Mao Y #, Zheng Y, Wen J, Song P, Xue Y, Wang W, Sang Y, Chen Y*, Dai C*. Extracapsular lymph node involvement is a robust survival predictor in esophageal cancer patients: A pooled analysis[J].Eur J Surg Oncol.2021,47(8):1875-1882.doi: 10.1016/j.ejso.2021.03.247.

6.Chen D#,Mao Y#, Chen Y*, Chen C.Clinical Thoughts on Mediastinal Node Management in Early-Stage Lung Cancer[J].J Thorac Oncol.2020, 15(11): e183-e184.doi: 10.1016/j.jtho.2020.06.023.

7.Xu X#,Mao Y#, Ding Q, Chen Y*.Clinical and Pathologic Implications of Tumor Genomics of Predominant Histologic Subtypes in Lung Adenocarcinoma[J].J Thorac Oncol.2020,15(12): e187-e188.doi: 10.1016/j.jtho.2020.08.027.

8.Chen D#, Xue Y#,Mao Y*, Chen Y*.Comment on "Prognostic Impact of Postoperative Lymph Node Metastases After Neoadjuvant Chemoradiotherapy for Locally Advanced Squamous Cell Carcinoma of Esophagus"[J].Ann Surg.2021,274(6):e767-e768.doi: 10.1097/SLA.0000000000004404

9.Chen D#, Wang X#, Zhang F#, Han R, Ding Q, Xu X, Shu J, Ye F, Shi L,Mao Y*, Chen Y*, Chen C*.Could tumor spread through air spaces benefit from adjuvant chemotherapy in stage I lung adenocarcinoma? A multi-institutional study[J].Ther Adv Med Oncol.2020,12:1758835920978147. doi: 10.1177/1758835920978147. eCollection 2020.

10.Wang W#, Chen D#, Sang Y#, Chen C, Zhang Y*,Mao Y*, Chen Y*. Endoscopic resection versus esophagectomy for patients with small-sized T1N0 esophageal cancer: A propensity-matched study[J].Clin Res Hepatol Gastroenterol.2021,45(3):101543.doi: 10.1016/j.clinre.2020.09.004.

11. Chen D#,Mao Y#, Wen J#, She Y, Zhu E, Zhu F, Zhang Y, Fan M, Chen C*, Chen Y*. Tumor Spread Through Air Spaces in Non-Small Cell Lung Cancer: A Systematic Re view and Meta-Analysis[J].Ann Thorac Surg.2019, 108(3): 945-954.doi: 10.1016/j.athoracsur.2019.02.045.

12. Song Y#, Li J#,Mao Y*, Zhang X*. ceRNAshiny: An Interactive R/Shiny App for Identification and Analysis of ceRNA Regulation[J].Front Mol Biosci.2022,9:865408.doi: 10.3389/fmolb.2022.865408.

13.Chen D#,Mao Y#, Xue Y, Sang Y, Liu D, Chen Y*.Does the lymph node yield affect survival in patients with esophageal cancer receiving neoadjuvant therapy plus esophagectomy? A systematic review and updated meta-analysis[J].EClinicalMedicine.2020,25:100431.doi:10.1016/j.eclinm.2020.100431.

14.茅怡铭,吴长江*.老年多发肋骨骨折患者肺部并发症风险预测模型的建立[J].上海交通大学学报（医学版）,2019, 39(1): 69-72.

15.茅怡铭*,魏长江,吴长江,秦元,陆佳昊,陆文强.电视辅助胸腔镜与常规切口肺减容术治疗重度慢性阻塞性肺疾病效果比较的meta分析[J].上海交通大学学报（医学版）,2017, 37(7): 997-1003.

16.茅怡铭,魏长江.肺内胸腺瘤1例[J].中华胸心血管外科杂志,2015, 31(10): 636.

17.Qin T#, Xiang W#,Mao Y#, Zhai H, Yang Z, Zhang H*. NcRNA-regulated CAPZA1 associated with prognostic and immunological effects across lung adenocarcinoma. Front Oncol. 2023 Jan 4;12:1025192. doi: 10.3389/fonc.2022.1025192.

18.Qiu H#,Shen L, Shen Y#,Mao Y#. Identification of a miRNA-mRNA regulatory network for post-stroke depression: a machine-learning approach. Front Neurol. 2023 Jul 17;14:1096911. doi: 10.3389/fneur.2023.1096911.

19.Yao Y#, Ji Z#, Pan W, Wu C#,Mao Y#.Letter to the editor for the article "Functional and surgical outcomes after phalloplasty in cis men". World J Urol. 2023 Dec;41(12):3921-3922. doi: 10.1007/s00345-023-04684-6. Epub 2023 Oct 30.

20.茅怡铭,徐莉,戴春雷*.老年早期肺腺癌患者术后切口愈合不良预测模型的建立[J]. 2023,29(1):58-62,67.

六、获奖情况

1. 中国非公医疗机构青年英才

2. 2022年姑苏卫生人才青年拔尖人才

3. 2018年上海交通大学非公立医院经营管理研究所•医院管理研究中心特聘研究员