一、基本信息

易晨龙，医学博士，博士后，主治医师，硕士生导师， 扬州大学附属医院心脏大血管中心， 邮箱：yichenlong_001@163.com

二、教育经历

2012.9—2015.7，南京医科大学，外科学（心胸外科）专业，硕士

2017.9—2020.7，苏州大学，医学院，外科学（心胸外科）专业，博士

2023.2—2025.2，宾夕法尼亚大学，医学院，基因与转化医学，博士后

三、研究方向

1，内皮细胞在心肺相关疾病模型中的研究；

2，心肌缺血再灌注损伤的保护；

3，传统中药对心肺疾病的作用及机制研究。

四、承担项目

1，国家自然科学基金青年科学基金项目，Calpains介导内皮细胞粘附连接障碍在机械通气肺损伤中的作用及机制研究，2022-01至2024-12，在研，主持；

2，扬州大学附属医院，优秀博士人才科研计划项目，机械通气肺损伤干预靶点及临床转化研究，2020-10至2025-10，在研，主持；

3，扬州市市级社会发展项目，靶向Calpain抑制体外循环肺损伤的临床转化研究，2022-07至2024-06，已结题，主持。

五、代表性论著

1.Song Q, Zhang C, Wang W, Wang C,Yi C.Exploring the genetic landscape of the brain-heart axis: A comprehensive analysis of pleiotropic effects between heart disease and psychiatric disorders. Prog Neuropsychopharmacology Biol Psychiatry. Published online October 17, 2024.

2. Wang W, Song Q, Wang Q, Zhang Z, Wang C,Yi C. Surgical Therapy for a Giant Coronary Sinus Thrombus Associated With Persistent Left Superior Vena Cava. Annals of Internal Medicine: Clinical Cases, 2024, 3(11): e240231.

3. Zhang D, Cleveland AH, Krimitza E, Han K,Yi C, Stout AL, Zou W, Dorsey JF, Gong Y, Fan Y. Spatial analysis of tissue immunity and vascularity by light sheet fluorescence microscopy. Nat Protoc. 2024 Apr;19(4):1053-1082.

4. Yi C,Chen F, Ma R, Fu Z, Song M, Zhang Z, Chen L, Tang X, Lu P, Li B, Zhang Q, Song Q, Zhu G, Wang W, Wang Q, Wang X. Serum level of calpains product as a novel biomarker of acute lung injury following cardiopulmonary bypass. Front Cardiovasc Med. 2022 Nov 16;9:1000761.

5. Yi C,Song M, Sun L, Si L, Yu D, Li B, Lu P, Wang W, Wang X. Asiatic Acid Alleviates Myocardial Ischemia-Reperfusion Injury by Inhibiting the ROS-Mediated Mitochondria-Dependent Apoptosis Pathway. Oxid Med Cell Longev. 2022 Feb 14;2022:3267450.

6. Li B, Ji Y,Yi C, Wang X, Liu C, Wang C, Lu X, Xu X, Wang X. Rutin Inhibits Ox-LDL-Mediated Macrophage Inflammation and Foam Cell Formation by Inducing Autophagy and Modulating PI3K/ATK Signaling. Molecules. 2022 Jun 29;27(13):4201.

7. Yi C, Wu W, Zheng D, Peng G, Huang H, Shen Z, Teng X. Targeted inhibition of endothelial calpain delays wound healing by reducing inflammation and angiogenesis. Cell Death Dis. 2020 Jul 14;11(7):533. doi: 10.1038/s41419-020-02737-x.

8. Yi C,Si L, Xu J, Yang J, Wang Q, Wang X. Effect and mechanism of asiatic acid on autophagy in myocardial ischemia-reperfusion injury in vivo and in vitro. Exp Ther Med. 2020 Nov;20(5):54.

9. Si L, Xu J,Yi C, Xu X, Ma C, Yang J, Wang F, Zhang Y, Wang X. Asiatic Acid Attenuates the Progression of Left Ventricular Hypertrophy and Heart Failure Induced by Pressure Overload by Inhibiting Myocardial Remodeling in Mice. J Cardiovasc Pharmacol. 2015 Dec;66(6):558-68.