一、基本信息

李广，男，1981年12月出生，主任医师，医学博士，副教授，硕士生导师，扬州大学附属医院，科副主任（主持工作），邮箱：entliguang@163.com

二、教育经历

1999.6—2004.7，扬州大学，医学院，临床专业，学士

2011.9—2014.7，扬州大学，医学院，外科专业，硕士

2017.9—2020.7，山东大学，医学院，耳鼻咽喉科专业，博士

三、研究方向

主要从事咽喉头颈肿瘤，耳聋相关研究

四、承担项目

1、3D剧幕虚拟仿真背景下咽拭子采集和电子喉镜检查方法的结果评价 2020年，主持

2、扬州市社会发展，SERS微流控技术在喉癌早期诊断中的应用研究，2023年，10万，主持

五、代表性论著

1. Li G, Pan C, Sun J, Wan G, Sun J. lncRNA SOX2-OT regulates laryngeal cancer cell proliferation, migration and invasion and induces apoptosis by suppressing miR-654. Exp Ther Med. 2020 May;19(5):3316-3324.

2. Li G, Cheng Z. miR-339-5p Inhibits Autophagy to Reduce the Resistance of Laryngeal Carcinoma on Cisplatin via Targeting TAK1. Biomed Res Int. 2021 Aug 3;2021:9938515.

 3. Li G, Niu P, Ge S, Cao D, Sun A. SERS Based Lateral Flow Assay for Rapid and Ultrasensitive Quantification of Dual Laryngeal Squamous Cell Carcinoma-Related miRNA Biomarkers in Human Serum Using Pd-Au Core-Shell Nanorods and Catalytic Hairpin Assembly. Front Mol Biosci. 2022 Feb 11;8:813007

4. Li G, Ge S, Niu P, Zhang J, Mao Y, Wang Y, Sun A. Simultaneous detection of circulating tumor DNAs using a SERS-based lateral flow assay biosensor for point-of-care diagnostics of head and neck cancer. Biomed Opt Express. 2022 Jul 5;13(8):4102-4117.

5. Ge S, Chen G, Deng J, Gu Y, Mao Y, Zhou X, Li G. Multiplex signal amplification strategy-based early-stage diagnosis of Parkinson's disease on a SERS-enabled LoC system. Anal Chim Acta. 2023 Mar 22;1247:340890.

6. Bao X, Wang S, Liu X, Li G. Highly sensitive detection of CYFRA21-1 with a SERS sensing platform based on the MBs enrichment strategy and antibody-DNA-mediated CHA amplification. Front Bioeng Biotechnol. 2023 Aug 10;11:1251595.

7、Guang Li, Xinyu Zhou, Shengjie Ge, Xiaotao Bao, Xiaoyan Liu, Aidong Sun. Highly sensitive miRNA detection of early-stage laryngeal carcinoma using a solid-state Au nanocone arrays fabricated LoC-SERS analysis system coupled with target-triggered dual cycle amplification strategy. Chemical Engineering Journal. 2023; 478, 147448.

六、获奖情况

1、2022年附院“青年名医”

2、2023年附院“科研之星”