一、基本信息

朱滢，女，1988年8月出生，医学博士，硕士生导师，苏北人民医院消化内科副主任医师，内镜中心副主任，邮箱：bujingzhuying@126.com。

二、教育经历

2006.9—2011.7，山东第一医科大学，临床医学专业，学士

2011.9—2014.7，南京医科大学，内科学，硕士

2017.9—2020.7，南京医科大学，内科学，博士

2021.12—2023.08,美国密歇根大学，内科学，博士后

三、研究方向

主要从事胃肠动力性疾病（胃食管反流病、便秘、功能性消化不良及肠易激综合征等）相关研究

四、承担项目

1. 国家自然科学基金青年基金项目“SphK1/S1P/FOXO1轴调控KATP通道介导胃平滑肌功能障碍在糖尿病胃轻瘫中的作用与机制研究”，项目批准号82400623，30万，主持

2. 江苏省中医药科技发展基金面上项目“从肠道微生态调节肠肌间巨噬细胞活化探讨针药联合治疗气虚型便秘的临床研究”，项目编号MS2023138，5万，主持

3. 江苏省自然科学基金青年项目“SphK1/S1P鞘磷脂信号调控KATP通道抑制胃平滑肌收缩在糖尿病胃轻瘫中的作用及机制”，项目编号BK20240498，20万，主持

4. 国家自然科学基金委员会青年项目“小电导钙激活钾通道3在雌二醇抑制结肠平滑肌收缩中的作用及机制”项目编号81400599，22.0万，已结题，参与

5. 江苏省科技厅，江苏省基础研究计划（自然科学基金）青年项目“鳖甲煎丸通过减少ITGβ1-EVs分泌抑制单核细胞黏附抗肝纤维化的作用机制研究”项目编号BK20200266，20.0万，结题，参与

6. 扬州市社发重点项目“基于单个B细胞的SARS-COV-2中和抗体快速制备和研究平台建设”YZ20201012020.07-2022.06，已结题，参与

7. 苏北人民医院院级基金项目“足三里联合内关经皮穴位电刺激治疗肝动脉介入栓塞化疗术后胃肠道症状”项目编号yzucms201922，已结题，1.0万，主持

五、代表性论著

1.Ying Zhu, Feng Xu, Chao Sun, Wenyi Xu, Miaomiao Li, Yaoyao Gong, Peijing Rong, Lin Lin, Jiande D.Z. Chen*. Noninvasive Transcutaneous Auricular Vagal Nerve Stimulation Improves Gastric Slow Waves Impaired by Cold Stress in Healthy Subjects, Neuromodulation. 2022; S1094-7159(22)00647-X

2. Ying Zhu, Feng Xu, Dewen Lu, Peijing Rong, Jiafei Cheng, Miaomiao Li, Yaoyao Gong, Chao Sun, Wei We, Lin Lin*, Jiande D.Z. Chen*. Transcutaneous auricular vagal nerve stimulation improves functional dyspepsia by enhancing vagal efferent activity, American Journal of Physiology-Gastrointestinal and Liver Physiology, 2021, 320(5): G700-G711

3. Ying Zhu, Xianpeng Li, Jibo Ma, Wenyi Xu, Miaomiao Li, Yaoyao Gong, Bo Zhang, Ying Chen, Sun Chao, Qingcheng Xu, Lin Lin*, Jiande D.Z. Chen*. Transcutaneous electrical acustimulation improves gastrointestinal disturbances induced by transcatheter arterial chemoembolization in patients with liver cancers, Neuromodulation, 2020, 23(8): 1180-1188

4. Jiande D.Z. Chen*, Ying Zhu, Yan Wang. Emerging noninvasive neuromodulation methods for functional gastrointestinal diseases, Journal of translational internal medicine, 2022, 10(4): 281-285

5. Yaoyao Gong, Ying Zhu, Boqian Zhu, Xinmin Si, Ding Heng, Yurong Tang, Xiaomeng Sun, Lin Lin*. LncRNA MALAT1 is up-regulated in diabetic gastroparesis and involved in high-glucose-induced cellular processes in human gastric smooth muscle cells. Biochem Biophys Res Commun. 2018; 496(2): 401-406.

6. Miaomiao Li, Feng Xu, Minjie Liu, Yinfang Li, Jingfei Zheng, Ying Zhu, Lin Lin*, Jiande D.Z. Chen*. Effects and Mechanisms of Transcutaneous Electrical Acustimulation on Postoperative Recovery After Elective Cesarean Section. Neuromodulation. 2020; 23(6): 838-846.

7. Ying Zhu#, Yaoyao Gong#, Xiaomeng Sun, Ping Li, Lin Lin*. Advanced glycation end products inhibit distal colon contraction in rats via protein kinase C-dependent modulation of intracellular calcium. Int J Clin Exp Med. 2016; 9(9): 18780-18789.

8.Xiaomeng Sun, Jiacheng Tan, Ying Zhu, Lin Lin*. Association between diabetes mellitus and gastroesophageal reflux disease: A meta-analysis. World J Gastroenterol. 2015; 21(10): 3085-3092.

9. Ping Li, Meilan Liang, Ying Zhu, Yaoyao Gong, Yun Wang, Ding Heng, Lin Lin*. Resveratrol inhibits collagen I synthesis by suppressing IGF-1R activation in intestinal fibroblasts. World J Gastroenterol. 2014; 20(16): 4648-4661.

六、获奖情况

1. Ying Zhu,Shiying Li,Shuangsong Hong,Jiande DZ Chen. Evidence of Duodenal Epithelial Barrier Impairment in a Rodent Model of Visceral Hyperalgesia Ameliorated by Auricular Vagus Nerve Stimulation.Digestive Disease Week 2023,Chicago, USA, 2023-05-09,口头交流（会议报告）

2. Ying Zhu,Shiying Li,Jahangir Alam,Yan Wang,Jiande DZ Chen.Cross-Branch Effects of Parasympathetic Nerve Stimulation on Ileal Inflammation in Rats, North American Neuromodulation Society 2023,Las Vegas,USA, 2023-01-12,口头交流（会议报告）

3. Ying Zhu, Feng Xu, Dewen Lu, Peijing Rong, Lin Lin, Jiande DZ Chen. Transcutaneous auricular vagal nerve stimulation improves functional dyspepsia by enhancing vagal efferent activity. North American Neuromodulation Society 2020, Las Vegas, USA, 2020-01-23,口头交流（会议报告）

4. Ying Zhu, Feng Xu, Dewen Lu, Lin Lin, Jiande DZ Chen. Transcutaneous auricular vagal nerve stimulation improves functional dyspepsia by enhancing vagal efferent activity. Digestive Disease Week 2019, San Diego, USA, 2019-05-18,口头交流（会议报告）

5. Ying Zhu, Feng Xu, Dewen Lu, Peijing Rong, Lin Lin, Jiande DZ Chen. Transcutaneous auricular vagal nerve stimulation improves functional dyspepsia by enhancing vagal efferent activity. International Gastrointestinal Electrophysiology Society 2019, San Diego, USA, 2019-05-18,口头交流（会议报告）

6. Ying Zhu, Xianpeng Li, Jibo Ma, Wenyi Xu, Lin Lin, Jiande DZ Chen. Transcutaneous electrical acustimulation improves gastrointestinal disturbances induced by transcatheter arterial chemoembolization in patients with liver cancers. Digestive Disease Week 2019, San Diego, USA, 2019-05-18,壁报交流（会议报告）

7. 朱滢，孙超，陈磊胃肠动力性疾病诊疗新策略的开发与应用，2021年度扬州市医学新技术二等奖，第一完成人（学术奖励）

8 . 孙超，朱滢，柴海娜 内镜下圈套器冷切除术在结直肠息肉治疗中的应用，2023年度扬州市医学新技术二等奖，第二完成人（学术奖励）

9. 刘昕，高巨，朱滢 优化麻醉管理策略在无痛消化道内镜患者ERAS中的建立及应用，2023年度扬州市医学新技术二等奖，第三完成人（学术奖励）