一、基本信息

孙扬永，男，1980年1月出生，医学博士，硕士生导师，镇江市第一人民医院（江苏大学附属人民医院），副科主任，副主任医师。镇江市“金山英才”医学领域高层次引进人才，镇江市“169”工程学术技术骨干，江苏省医师协会心血管外科医师委员，江苏省研究型医院协会心血管内外科一体化专业委员会委员，江苏省医学会心血管外科学大血管外科学组成员，江苏省医学会心血管外科学先心病学组成员。擅长心脏瓣膜疾病、冠心病、急慢性主动脉夹层、先天性心脏病等心血管疾病及食管疾病、肺癌、肺结节、纵隔肿瘤等常见普胸疾病的诊断治疗。常规开展体外循环下二尖瓣置换/修复、主动脉瓣置换、三尖瓣成形、冠状动脉旁路移植、先天性心脏病的矫治，DSA下主动脉腔内覆膜支架植入术，胸腔镜下食管癌根治术，胸腔镜下肺叶切除术，肺段切除术等。参与多项国自然基金项目、上海市自然科学基金项目等，主持镇江市科技局项目一项。邮箱：sunyangyong0116@163.com

二、教育经历

1999.9—2004.7，江苏大大学，医学院，临床专业，学士

2004.9—2007.7，江苏大学，医学院，外科学专业，硕士

2019.9—2022.7，海军军医大学（第二军医大学），外科学专业，博士

三、研究方向

主要从事心脏大血管疾病的发表机制以及相关药物治疗的研究

四、承担项目

镇江市科学技术局“靶向MKNK2的小分子化合物SM1-71-plus改善糖尿病心肌损伤的作用和药效评价”。项目号：JC2024032，2024/08-2026/8，4万，主持

五、代表性论著

1. Zhao An^#,Yangyong Sun^#,Xiaodong Yang^#,Jingwen Zhou, Yongchao Yu Boyao Zhang, Zhiyun Xu,Yuming Zhu,Guokun Wang.Enhanced expression of miR-20a driven by nanog exacerbated the degradation of extracellular matrix in thoracic aortic dissection. Non-coding RNA Research.2024 May 09.doi.org/10.1016/j.ncrna.2024.05.006.

2. Sun YY,Li S, Liu C, Pan Y, Xiao Y. Identification of a methyltransferase-related long noncoding RNA signature as a novel prognosis biomarker for lung adenocarcinoma. Aging (Albany NY). 2024 May 20;16(10):8747-8771. doi: 10.18632/aging.205837. Epub 2024 May 20. PMID: 38771129; PMCID: PMC11164517.

3. Sun Y^#, Wang H^#, Xu H^#, Xu X, Wang G^*, Xu Z^*. Outcomes of reoperation for total arch replacement combined with frozen elephant trunk after previous cardiovascular surgery. Asian J Surg. 2023;46(1):314-320.

4. Xu H, Wang H, Wu L, Xu T, Han L, Lu F, Li B,Sun Y*, Xu Z*. Prognostic Value of Systemic Inflammation Response Index in Acute Type A Aortic Dissection. World J Surg.2023;47(10):2554-2561.

5. An Z^#, Zhong K^#,Sun Y^#, Han L, Xu Z, Li B. Risk factors for in-hospital mortality after total arch procedure in patients with acute type A aortic dissection.Front Cardiovasc Med. 2023;10:1149907.

6. Yu M^#,Sun Y^#, Shan X^#, Yang F, Chu G, Chen Q, Han L, Guo Z^*, Wang G^*. Therapeutic overexpression of miR-92a-2-5p ameliorated cardiomyocyte oxidative stress injury in the development of diabetic cardiomyopathy. Cell Mol Biol Lett. 2022;27(1):85.

7. Xu H^#, Li Y^#, Wang H^#, Yuan Y, Chen D,Sun Y^*, Xu Z^*. Systemic immune-inflammation index predicted short-term outcomes in ATAD patients undergoing surgery. J Card Surg. 2022;37(4):969-975.

8. Xu H^#, Wang H^#, Chen S^#, Chen Q, Xu T, Xu Z^*,Sun Y^*. Prognostic Value of Modified Model for End-Stage Liver Disease Score in Patients Undergoing Isolated Tricuspid Valve Replacement. Front Cardiovasc Med. 2022;9:932142.

9. Sun Y^#, Xu H^#,Xu X^#, Wang H^#, Yuan Y, An Z, Xu Z^*, Wang G^*. A novel method to obtain rat aortic media for primary culture of rat aortic smooth muscle cells. In Vitro Cell Dev Biol Anim. 2021;57(7):726-734.

10. Sun Y^#, Yang F^#, Liu Y^#, Yu M, Wu F^*, Wang G^*. Di-2-ethylhexyl phthalate induces heart looping disorders during zebrafishdevelopment.2021;37(7):391-397.

11. An Z,Sun YY, Fan RX, Yu SQ, Zhu JM, Han QQ, Han L. Extensive Arch Repair with a Novel Two-Branched Stent Graft in Acute Type A Aortic Dissection. Ann Thorac Cardiovasc Surg. 2022;28(4):255-261.

12. YuanY,Sun Y, Li N, Han L, Lu F, Li B, Xu Z. Long-Term Outcomes of Bioprosthetic and Mechanical Tricuspid Valve Replacement after Left-Sided Valves Surgery. Ann Thorac Cardiovasc Surg. 2023;29(6):307-314.

13. Wang H,Sun Y, Peng J, Zhao L, Xu H, Xu Z, Zhang G. An Analysis of Total Arch Re-Replacement After Proximal Aortic Surgery. Heart Surg Forum. 2022;25(4):E616-E620.

14. Li Q, Gao Y, Zhang J, Tang Y,Sun Y, Wu L, Wu H, Shen M, Liu X, Han L, Xu Z.Crosslinking and functionalization of acellular patches via the self-assembly of copper@tea polyphenol nanoparticles.Regen Biomater. 2022:9:rbac030.

15. 孙扬永,王国坤,徐志云.腹主动脉瘤发病的细胞学机制[J].江苏医药,2021,47(07):736-738.

16. 李芹,孙扬永,吴昊,刘晓红,徐志云.茶多酚处理脱细胞牛心包组织支架作为人工食管修补材料的可行性.中国组织工程研究，27(12):1832-1836[2022-04-02

六、获奖情况

1. 2022年镇江市“金山英才”医学领域高层次引进人才；

2. 2023年镇江市“169”工程学术技术骨干；