一、基本信息

杨春喜，男，1976年3月出生，医学博士，副主任医师，硕士生导师，南通瑞慈医院(兼职)，上海交通大学医学院附属仁济医院，邮箱：chunxi_yang@163.com

二、教育经历

1996.9-2000.5，河北医科大学，临床医学专业，大专

1997.9-2001.1，河北广播电视大学，英语专业，大专

2002.9—2005.5，承德医学院，临床医学专业，学士

2004.9—2007.7，郑州大学，医学院，外科专业，硕士

2007.9—2010.7，上海交通大学，医学院，外科专业，博士

三、研究方向

主要从事肩关节外科临床与相关研究

四、承担项目

1. 国家自然科学基金面上项目，“Mg-MBG-Asp8@KGN复合光敏水凝胶靶向释放Mg2+和KGN促进肩袖损伤后腱-骨愈合的机制”，892372488，2024/01-2027/12，49万，主持

2. 国家自然科学基金青年基金项目，“镁离子对成人骨髓间充质干细胞外基质矿化的作用和机制”，81101344/HO604，2012/01-2014/12，22万元，主持

3. 上海市卫健委面上项目，“复合Cu-Li生物玻璃的多功能一体化水凝胶促进肩袖损伤腱-骨愈合机制的研究”，20224022，2023/01-2025/01，10万元，主持

4. 上海市科委面上项目，“X线平片诊断膝关节外侧盘状半月板的方法和优化”，16411971700，2016/07-2019/06，20万，主持

5. 南通大学医学院教改课题，“探索转化医学引导对高年级医学本科生科研能力的影响”，2016，0.3万元，主持

6. 宁波市自然科学基金面上项目，“Mg²⁺调控软骨细胞外基质钙化过程的P2X/P2Y关键亚型的筛选研究”，2019A610240，2019/04-2022/03，10万元，主持

7. 同济大学交叉学科课题，“通过二维微层共挤出技术研发富镁、钙可修复肌腱的PLA功能型纳米纤维”，1501219095，2015/07-2016/12，20万，主持

五、代表性论著

1. Yang Chunxi, Xie Cheng, Liu Hui, Hua Zikai, An Bingchen (2022) Mechanical mechanism of suture passer needle break in rotator cuff repair.Front. Surg.9:1065666. doi: 10.3389/fsurg.2022.1065666

2. Li Yaqiang, Xun Xiaowei, Xu Yong, Zhan Anqi, Gao Erji, Yu Fan, Wang You, Luo Honglin,Yang Chunxi. Hierarchical porous bacterial cellulose scaffolds with natural biomimetic nanofibrous structure and a cartilage tissue-specific microenvironment for cartilage regeneration and repair. Carbohydrate Polymers. 276 (2022) 118790.通讯作者

3.Fu Zhiwei, Xu Changming, Wang You, Qu Xinhua,Yang Chunxi. Traditional Chinese Acupressure Massage of the Quadriceps Femoris Can Relieve Flexion Pain after Undergoing Total Knee Arthroplasty. Evidence-Based Complementary and Alternative Medicine. 2022, 1091174.通讯作者

4. YangJiajie, Li,Yaqiang,ShiXiaojian, ShenMeihua, ShiKaibing, ShenLingjie, YangChunxi. Design and analysis of three-dimensional printing of a porous titanium scaffold.BMC Musculoskelet Disord.2021; 22: 654. 通讯作者

5. Li Xibai, Sun Yan, Jiao Juyang, Wu Haoyu,YangChunxi,Yang Xubo. Automatic Discoid Lateral Meniscus Diagnosis from Radiographs Based on Image Processing Tools and Machine Learning. J Healthc Eng. 2021: 6662664. 通讯作者

6. Li Yaqiang, Wang Jing, Yue Jiaji, Wang Yu,Yang Chunxi, Cui Quanjun. High magnesium prevents matrix vesicle-mediated mineralization in human bone marrow-derived mesenchymal stem cells via mitochondrial pathway and autophagy. Cell Biol Int. 2018, 42(2):205-215. 通讯作者

7. Yue Jiaji, Ma Xiaojun, Li Yaqiang, Wang Yu,Yang Chunxi, Zhu Yuchang. Influence of Bone Marrow Edema on Medial Unicompartmental Knee Arthroplasty among Patients with Patellofemoral Osteoarthritis. J Knee Surg. 2017;30(8):816-21. 通讯作者

8. Yue J, Jin S, Li Y, Zhang L，Jiang W，Yang C，Du, J. Magnesium inhibits the calcification of the extracellular matrix in tendon-derived stem cells via the ATP-P2R and mitochondrial pathways. Biochem Biophys Res Commun. 2016, 478(1):314-322. 通讯作者

9. Jiang Wenwei, Li Xifan, Su Hang,Yang Chunxi. A new method to diagnose discoid lateral menisci on radiographs. Knee Surg Sports Traumatol Arthrosc. 2016 24:1519–1524.通讯作者

10. Yue Jiaji, Zhang Li,Yang Chunxi. The impact of patellofemoral arthritis on unicompartmental knee arthroplasty.Acta Orthop Belg. 2015 Dec;81(4):587-93. 通讯作者

11. Yang Chunxi,Madhu V, Thomas C, Yang X, Du X, Dighe AS, Cui Q. Inhibition of differentiation and function of osteoclasts by dimethyl sulfoxide (DMSO). Cell Tissue Res. 2015, 12;362(3):577-85.

12. Li Zhang,Chunxi Yang, Jiao Li, Yuchang Zhu, Xiaoling Zhang. High extracellular magnesium inhibits mineralized matrix deposition and modulates intracellular calcium signaling in human bone marrow-derived mesenchymal stem cells. Biochemical and Biophysical Research Communications 450 (2014), 1390-1395.通讯作者.

13. Chunxi Yang, Guangyin Yuan, Jia Zhang, Ze Tang, Xiaoling Zhang, Kerong. Effects of magnesium alloys extracts on adult human bone marrow-derived stromal cell viability and osteogenic differentiation. Biomedical Materials. 2010.5 045005.

14. Chunxi Yang, Chuan Gao, Yizao Wan, Tingting Tang, Shuhong Zhang, Kerong Dai. Preparation and Characterization of Three-Dimensional Nanostructured Macroporous Bacterial Cellulose/Agarose Scaffold for Tissue Engineering. Journal of Porous Materials. 2011,18:545-552.

15. 杨春喜,殷宁,戴尅戎.转化医学.中华医学杂志. 2010, 2, 23 90(7): 499-502.