
一、基本信息
何春燕,女,1984年4月出生,医学博士,副教授,硕士生导师,昆山市中医医院,邮箱:34698925@qq.com.
二、教育经历
2001.6—2006.7,吉林大学,护理学院,护理专业,学士
2006.9—2008.7,吉林大学,基础医学院,免疫学专业,硕士
2008.9—2011.12,吉林大学,基础医学院,免疫学专业,博士
三、研究方向
主要从事自身免疫性疾病发病机制相关研究
四、承担项目
1、国家自然科学基金青年基金项目“微粒(Microparticles)在狼疮肾炎发病中的作用及其潜在信号通路的研究”项目号:81202348,2013/01-2015/12,23万,主持
2、江苏省自然科学基金青年项目,“微粒在狼疮肾炎发病中的作用及其潜在信号通路的研究”项目号:BK2012171,2012/07-2015/06,40万,主持
3、江苏省自然科学基金面上项目,“活性氧促进蛋白激酶A信号通路在金黄色葡萄球菌诱导血小板凋亡中的作用”,项目号:BK20181171,2018/07-2021/06,20万,主持
4、苏州市重点病种诊疗专项,“结直肠癌早期精准诊断技术研发及临床应用研究”,项目号:LCZX202230,2023/01-2025/12,60万,主持
五、代表性论著
1. He, Chunyan,Zhao, Lian,Nie, Yumei,Yan Rong,Zhou Kangxi,Li Xiaodong, Zhou Birong, Dai Kesheng,A novel method to detect autoantibodies against platelets in patients with immune thrombocytopenia. Clin Chim Acta,2020,511:90~93
2. Zhao, Lili, Liu, Jun, He, Chunyan, Yan, Rong, Zhou, Kangxi, et al. Protein kinase A determines platelet life span and survival by regulating apoptosis. J Clin Invest. 2017;127(12):4338–51.
3. He, Chunyan,Feng, Ping,Su, Honghong,Gu, Aiping,Yan, Zhaowei,Zhu, Xueming,Disrupted Th1/Th2 balance in patients with rheumatoid arthritis (RA),Int J Clin Exp Pathol,2017,10(2):1233~1242
4. He, Chunyan,Mao, Ting,Feng, Yanhua,Song, Tiantian,Qin, Chenhao,Yan, Ruhong,Feng, Ping,Anti-CII antibody as a novel indicator to assess disease activity in systemic lupus erythematosus,Lupus,2015,24(13):1370~1376
5. He, Chunyan,Chen, Xiaohui,Zhao, Chunyang,Qie, Yanyan,Yan, Zhaowei,Zhu, Xueming,Eleutheroside E Ameliorates Arthritis Severity in Collagen-Induced Arthritis Mice Model by Suppressing Inflammatory Cytokine Release,Inflammation,2014,37(5):1533~1543
6. He, Chunyan,Lu, Xuehong,Yan, Zhaowei,Wu, Man,Liu, Shujun,Yu,Yongli,Luo, Ping,Therapeutic effect of leflunomide on the development of experimental lupus nephritis in Mice, Rheumatology International: Clinical and Experimental Investigations,2012,32(3):633~638
7. He, Chunyan,Zhou, Lei,Sun, Ran,Zhao, Tiesuo,Zhang, Yongsheng,Fu, Yao,Wang, Liying,Yu, Yongli,Effects of oligodeoxynucleotide with CCT repeats on chronic graft versus host disease induced experimental lupus nephritis in mice,Clinical Immunology,2011,140(3):300~30
8. He, Chunyan,Wang, Hua,Wei, Hongfei,Yan, Youyou,Zhao, Tiesuo,Hu, Xiaoping,Luo, Ping,Wang, Liying,Yu, Yongli,A recombinant truncated FMDV 3AB protein used to better distinguish between infected and vaccinated cattle,Vaccine,2010,28(19):3435~3439
9. Yan, Zhaowei,Xiong, Jianbin,Zhao, Chunyang,Qin, Chenhao,He, Chunyan,Decreasing cartilage damage in a rat model of osteoarthritis by intra-articular injection of deoxycholic acid,International Journal of Clinical and Experimental Medicine,2015,8(6):9038~9045
10. Yan Zhaowei,Dong, Ji,Qin Chenhao,Zhao Chunyang,Miao Liyan,He Chunyan,Therapeutic Effect of Chenodeoxycholic Acid in an Experimental Rabbit Model of Osteoarthritis,Mediators of Inflammation,2015,1(1):11~17
六、获奖情况
1、江苏医学科技奖三等奖,TWEAK在狼疮肾炎发病机制中的作用及其靶基因治疗的实验研究,2019(2/7)
2、苏州医学科技奖二等奖,TWEAK在狼疮肾炎发病机制中的作用及其靶基因治疗的实验研究,2019(2/7)
3、授权发明专利,ZL201410088157.4,刺五加苷E在制备治疗类风湿关节炎药物中的应用,2016(1/4)
4、2017年江苏省医学重点人才;
5、2020年姑苏卫生人才;