一、基本信息

华飞，男，1970年11月出生，医学博士，教授，博士生导师，常州市第一人民医院（苏州大学附属第三医院）党委副书记、院长，邮箱：huafei1970@suda.edu.cn

二、教育经历

1988.9—1993.7，苏州医学院，临床医学系，临床医学专业，学士

1999.9—2002.6，苏州大学，研究生院，临床医学专业，硕士

2010.9—2016.6，苏州大学，研究生院，临床医学专业，博士

三、研究方向

主要从事胰岛素抵抗相关疾病的基础与临床研究

四、承担项目

1、常州市科技局应用基础研究项目，《基于AGEs/RAGE信号通路研究维生素D在PCOS发病中的作用》，CJ20159019，2015/04～2018/03，5万，主持。

2、常州市卫计委重大科技项目，《基于区域医疗联合体的慢性病移动健康管理》，ZD201512，2016/01～2018/12，5万，主持。

3、江苏省社会发展项目，《基于“三位一体”慢病管理模式和云计算移动医疗健康信息平台的脑卒中危险因素筛查防控研究》，BE2016659，2016/06～2019/12，80万，主持。

4、常州市卫生领军人才，2016/01～2020/12，75万，主持。

5、江苏省妇幼健康科研项目，《多囊卵巢综合征患者综合干预模式的构建与评价》，F201803，2019/01～2021/12，3万，主持。

6、江苏省六大人才高峰项目，《维生素D通过下调AMH改善多囊卵巢综合征》，WSW-183，2019/01～2021/12，10万，主持。

7、常州市科技局社会发展项目，《基于物联网和人工智能的脑卒中危险因素管理模式研究》，CE20195042，2019.05～2021.05，10万，主持。

五、代表性论著

[1] Xiang SK,Hua F (通讯作者), Tang Y, Jiang XH, Zhuang Q, Qian FJ. Relationship between Serum Lipoprotein Ratios and Insulin Resistance in Polycystic Ovary Syndrome. Int J Endocrinol, 173281, 2012.

[2]Xiang S,Hua F(通讯作者), Chen L, Tang Y, Jiang X, Liu Z. Lipid accumulation product is related to metabolic syndrome in women with polycystic ovary syndrome Exp Clin Endocrinol Diabetes, 2013, 121(2): 115-118.

[3]Hua F, Yang C, Zhu B. Leptin: new hope for the treatment of post-operative cognitive dysfunction? Med Sci Monit, 2014, 20:866-868.

[4]Hua F, Yang C, Zhu B, Wu J. How to treat type 2 diabetes-induced encephalopathy: regulating the autophagic pathway? Nutrition, 2015, 31(7-8): 1055.

[5]Yang C, Zhu B,Hua F (通讯作者). Leptin deficiency is involved in the cognitive impairment of streptozocin-induced diabetic rats undergoing cardiopulmonary bypass Int J Clin Exp Med, 2014, 7(9): 2571-2577.

[6]Wang Z G, Yang C, Zhu B,Hua F (通讯作者). AMPK-dependent autophagic activation is probably involved in the mechanism of resveratrol exerting therapeutic effects for Alzheimer's disease Rejuvenation research, 2015, 18(1): 101-102.

[7]Xiang S, Wu Y, Wang L,Hua F (通讯作者). Vitamin D supplementation for depression in women with polycystic ovary syndrome: killing two birds with one stone? Archives of women's mental health, 2015, 18(5): 743-744.

[8]Zhu B, Yang C, Wu J, Hua F (通讯作者). Autophagic activation may be involved in the mechanism of hesperidin's therapeutic effects on cognitive impairment J Neurol Sci, 2015, 351(1-2): 202-203.

[9]Zhu B, Yang C,Hua F(通讯作者). Leptin disturbance probably involved in the pathogenesis of obesity-induced depressive symptoms. Maturitas, 2015,80(3):335.

[10]Xiang SK, Wan JB, Jiang XH, Zhu YH, Ma JH, Hua F(通讯作者). Effect of intravenous glucose tolerance test on bone turnover markers in adults with normal glucose tolerance. Med Sci Monit, 2016, 22:2602-2607.

[11]Zhu B,Hua F(通讯作者), Yang C. Disturbance of autophagic pathway may be involved in the diabetes-induced oxidative response in brain. Hum Exp Toxicol, 2016, 35(7):793.

[12]Huang JZ, Wu J, Xiang S, Sheng S, Jiang Y, Yang Z, Hua F (通讯作者). Catalpol preserves neural function and attenuates the pathology of Alzheimer's disease in mice Mol Med Rep, 2016, 13(1): 491-496.

[13] Tao L, Wang L, Yang X, Jiang X,Hua F (通讯作者). Recombinant human glucagon-like peptide-1 protects against chronic intermittent hypoxia by improving myocardial energy metabolism and mitochondrial biogenesis. Mol Cell Endocrinol, 2019, 481: 95-103.

[14] Zhang M, Jiang X, Qu M, Gu H, Sha Q,Hua F (通讯作者). Salubrinal abrogates palmitate-induced leptin resistance and endoplasmic reticulum stress via nuclear factor kappa-light-chain-enhancer of activated B cell pathway in mHypoE-44 hypothalamic neurons. Diabetes Metab Syndr Obes, 2018, 11: 893-899.

[15] Huang JZ, Ren Y, Xu Y, Chen T, Xia TC, Li ZR, Zhao JN,Hua F (通讯作者)., Sheng SY, Xia Y. The delta-opioid receptor and Parkinson's disease. CNS Neurosci Ther 2018, 24(12): 1089-1099.

[16] Tao L, Shi J, Yang X, Yang L,Hua F (通讯作者). The Exosome: a New Player in Diabetic Cardiomyopathy. J Cardiovasc Transl Res. 2019, 12(1):62-67.

[17] Yu F, Han W, Zhan G, Li S, Xiang S, Zhu B, Jiang X, Yang L, Luo A,Hua F (通讯作者), Yang C. Abnormal gut microbiota composition contributes to cognitive dysfunction in streptozotocin-induced diabetic mice. Aging (Albany NY). 2019, 11(10):3262-3279.

[18] Yu F, Han W, Zhan G, Li S, Jiang X, Xiang S, Zhu B, Yang L, Hua D, Luo A,Hua F(通讯作者), Yang C. Differential levels of Hippo signaling in selected brain and peripheral tissues in streptozotocin-induced cognitive dysfuntion in mice. Neuroscience. 2019, 421:48-58.

[19] Yu F, Han W, Zhan G, Li S, Jiang X, Wang L, Xiang S, Zhu B, Yang L, Luo A,Hua F(通讯作者), Yang C. Abnormal gut microbiota composition contributes to the development of type 2 diabetes mellitus in db/db mice[J]. Aging, 2019, 11(22): 10454-10467.

[20] Tao L, Yang L, Huang X,Hua F (通讯作者), Yang X. Reconstruction and analysis of the lncRNA-miRNA-mRNA network based on competitive endogenous RNA reveal fuctional lncRNA in dilated cardiomyopathy. Front Genet. 2019, 10:1149.

[21] Huang X, Jiang X, Wang L, Chen L, Wu Y, Gao P,Hua F(通讯作者).Visceral adipose accumulation increased the risk of hyperuricemia among middle-aged and elderly adults: a population-based study. J Transl Med. 2019, 17(1):341-350.

[22] Xiang S, Qi L, Zhao F, Wang W, Zhang X, Hu Y,Hua F (共同通讯作者), Zhang Z. Glucagon-like peptide-1 receptor gene polymorphism is associated with fat mass in Chinese nuclear families with male offspring. Acta Biochim Biophys Sin (Shanghai). 2019, 51(5):545-547.

[23] Tao L, Huang X, Xu M, Yang L,Hua F (通讯作者). Mir-44 preotects the heart from hyperglycemia-induced injury by regulating mitochondrial biogenesis and cardiomyocyte apoptosis. FASEB J. 2020, 34(2):2173-2197.

六、获奖情况

1、2013年，江苏省卫生厅医学新技术引进奖二等奖，排名第一。

2、2013年，江苏省五一劳动奖章。

3、2020年，苏州大学周氏教育科研奖。